25岁主播头痛到“天旋地转”,一查竟是因为把咖啡当水喝!医生:这不是提神,是透支The 25-year-old anchor had a headache that was so overwhelming that it turned out to be because he drank coffee like water! Doctor: This is not refreshing, it's overdrawn

2026-08-25 08:00:06 admin 2346
25岁的小雨(化名)是一名电商主播,工作时间基本从晚上持续到凌晨。为了扛住高强度节奏,她长期靠功能性饮料和咖啡提神,几乎每天都要喝上好几瓶。

几个月前,她开始出现严重的头晕头痛症状,发作时感觉天旋地转,直播状态严重受影响,到浙江省中山医院神经内科胡新平副主任处就诊时,胡主任发现她不仅存在紧张性头痛,还伴有明显的焦虑情绪和睡眠障碍。

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(图片由AI生成)

经过评估,胡主任为她开具了镇静和抗焦虑药物,同时给出关键建议:调整作息、减少功能饮料和咖啡的摄入。
胡主任说,像小雨这样的年轻患者并非个例。很多人觉得功能饮料和咖啡能提神抗疲劳,却不知道这种“提神”的背后,大脑正在发生什么。
“精神百倍”的假象:
不是精力变多,只是疲劳信号被屏蔽了
要理解功能饮料和咖啡的提神作用,得先认识一个关键物质——腺苷。
人清醒的时间越长,大脑细胞外的腺苷浓度就越高。腺苷和神经元上的受体结合后,会产生镇静和促眠效应——你越困,腺苷浓度越高,这是大脑最基本的自我保护机制。
而咖啡因的化学结构跟腺苷高度相似,能抢在腺苷之前和受体结合,却不会产生镇静效果。它就像一把“假钥匙”插进了锁孔,真正的腺苷反而被挡在外面,大脑接收不到疲劳信号。
喝完之后感觉精神百倍,并不是精力变多了,而是疲劳信号被暂时屏蔽了。疲劳还在,只是你暂时感觉不到了。

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(图片由AI生成)

越喝越没效、一停就更累?
大脑正在“加班生产”受体
长期摄入咖啡因,大脑会产生神经适应性变化——腺苷受体的数量会代偿性上调。你每天堵住一部分受体,大脑就再生产更多受体来维持正常的疲劳信号传导。
结果就是:耐受性形成——以前一瓶能顶半天,现在喝两瓶都没感觉。
一旦停用,所有新增的受体同时被腺苷占领,疲劳感加倍反扑,出现头痛、嗜睡、注意力涣散等戒断症状。
更值得警惕的是,功能饮料中的牛磺酸和咖啡因联合作用时,会显著增加大脑前额叶皮层和海马体的自由基生成——这两个区域分别负责决策功能和记忆形成。长期叠加,小雨又昼夜颠倒、睡眠紊乱,大脑既得不到夜间修复,又被持续强制兴奋,最终导致了严重的头痛、焦虑和失眠。
每天喝多少算过量?
这几类人最该管住嘴
胡主任表示,健康成年人每日咖啡因摄入量不宜超过400毫克,大约相当于两杯大杯美式咖啡。超过这个剂量,风险就开始显现。
研究发现,每天饮用超过6杯咖啡的人,脑容量更小,痴呆风险比每天1到2杯的人高出约53%。咖啡因具有脑血管收缩作用,长期高剂量摄入可能影响脑血流量的稳定调节。

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(图片由AI生成)

这几类人要特别当心:
本身有焦虑、失眠倾向的人——咖啡因会直接加重症状
作息不规律、长期熬夜的人——睡眠节律已经紊乱,再叠加兴奋剂只会让大脑更“崩溃”
对咖啡因敏感的人——喝一点就心慌手抖,说明代谢能力较弱,更要控制
小雨经过药物干预和饮食调整后,头痛头晕明显改善。但胡主任强调:药物只是帮过急性期,真正的核心是回归规律作息。
疲劳是大脑发出的真实信号,靠兴奋成分硬扛过去,不是在解决问题,只是在掩盖问题。大脑真正需要的,是规律的睡眠、均衡的营养、适度的活动——没有捷径,也没有哪一瓶饮料能替代得了。
转自:浙江省中山医院
来源:西湖之声

Xiaoyu (pseudonym), 25 years old, is an e-commerce anchor who works from night to early morning. In order to withstand high-intensity rhythms, she relies on functional drinks and coffee to stay alert for a long time, drinking several bottles almost every day.

A few months ago, she began to experience severe dizziness and headache symptoms, feeling dizzy and disoriented during attacks. Her live streaming status was severely affected. When she went to the neurology department of Zhongshan Hospital in Zhejiang Province for treatment, Director Hu found that she not only had tension headaches, but also had obvious anxiety and sleep disorders.

(The image is generated by AI)

After evaluation, Director Hu prescribed her sedatives and anti anxiety drugs, and provided key recommendations: adjusting her daily routine, reducing the intake of functional drinks and coffee.

Director Hu said that young patients like Xiaoyu are not isolated cases. Many people think that functional drinks and coffee can refresh and relieve fatigue, but they don't know what is happening in the brain behind this "refreshing" feeling.

The illusion of being mentally refreshed:

It's not that my energy has increased, it's just that the fatigue signal has been blocked

To understand the refreshing effects of functional drinks and coffee, one must first recognize a key substance - adenosine.

The longer a person stays awake, the higher the concentration of adenosine outside the brain cells. After binding to receptors on neurons, adenosine produces sedative and sleep promoting effects - the more tired you are, the higher the concentration of adenosine, which is the most basic self-protection mechanism of the brain.

The chemical structure of caffeine is highly similar to adenosine, which can bind to receptors before adenosine, but does not produce sedative effects. It's like a 'fake key' inserted into a lock, while the real adenosine is blocked and the brain cannot receive fatigue signals.

After drinking it, I feel refreshed, not because my energy has increased, but because the fatigue signal has been temporarily blocked. The fatigue is still there, you just can't feel it temporarily.

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Is drinking more ineffective and stopping more tiring?

The brain is working overtime to produce receptors

Long term intake of caffeine can cause neuroadaptive changes in the brain - compensatory upregulation of adenosine receptors. If you block a portion of the receptors every day, the brain will produce more receptors to maintain normal fatigue signal transduction.

The result is: tolerance formation - previously one bottle could hold for half a day, now drinking two bottles doesn't feel anything.

Once discontinued, all newly added receptors are simultaneously occupied by adenosine, leading to increased fatigue and withdrawal symptoms such as headache, drowsiness, and lack of attention.

What is even more alarming is that the combination of taurine and caffeine in functional drinks significantly increases free radical generation in the prefrontal cortex and hippocampus, which are responsible for decision-making function and memory formation, respectively. Long term accumulation, light rain and day night reversal, sleep disorders, the brain not only cannot be repaired at night, but also constantly forced to be excited, ultimately leading to severe headaches, anxiety, and insomnia.

How much is considered excessive drinking per day?

These types of people should keep their mouths shut the most

Director Hu stated that the daily intake of caffeine for healthy adults should not exceed 400 milligrams, which is approximately equivalent to two large cups of American coffee. Beyond this dosage, the risk begins to manifest.

Research has found that people who drink more than 6 cups of coffee per day have smaller brain capacity and a risk of dementia about 53% higher than those who drink 1 to 2 cups per day. Caffeine has a vasoconstrictive effect on cerebral blood vessels, and long-term high-dose intake may affect the stable regulation of cerebral blood flow.

(The image is generated by AI)

These types of people should be particularly careful:

People with anxiety and insomnia tendencies - caffeine can directly worsen symptoms

People with irregular sleep patterns and long-term staying up late - their sleep rhythm is already disrupted, and adding stimulants will only make the brain more "collapsed"

People who are sensitive to caffeine - if they feel anxious and shaky after drinking a little, it indicates that their metabolic capacity is weak and they need to control it even more

After medication intervention and dietary adjustments, Xiaoyu's headache and dizziness were significantly improved. But Director Hu emphasized that medication only helps during the acute phase, the real core is to return to a regular schedule.

Fatigue is a real signal emitted by the brain, which is carried over by excitatory components, not solving problems, but just masking them. What the brain really needs is regular sleep, balanced nutrition, and moderate activity - there are no shortcuts, and no bottle of beverage can replace them.

Transferred from: Zhongshan Hospital, Zhejiang Province

Source: Voice of West Lake

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